Dolichyl phosphate derivatives with a fluorescent label at an internal isoprene unit

摘要

A general approach based on directed aldol condensation followed by reductive amination with fluorescent amines and phosphorylation was developed and illustrated by the synthesis of two dolichyl phosphate derivatives with the 1-aminonaphthalene fluoro-phore at the gamma-isoprene unit of the chain. [References: 14]