Pyrido[2,3-b]- and pyrimido[4,5-b]quinoxalines: the first fluorine-containing derivatives

摘要

Fluorinated derivatives of pyrido[2,3-b]- and pyrimido[4,5-b]quinoxalines 5-8 have been prepared through the condensation of 2-amino-3-cyano- and 2-amino-3-aminocarbonyl-substituted 6-fluoro-7-R-quinoxalines 1-4 with dimethyl acetylenedicarboxylate and triethyl orthoformate, respectively. [References: 15]