A novel transformation of 2-acetylthiophene and its halogen derivatives under Vilsmeier reaction conditions

摘要

Under conditions of the Vilsmeier reaction either beta-chloro-beta-(2-thienyl)acrylic aldehydes or N,N-dimethyl-2-thiophenecarboxamides can be synthesised from 2-acetylthiophenes depending on the reaction temperature and time. [References: 20]