FIA-FIuorimetric Assembly for the Determination of Noradrenaline Hydrochloride by a Solid-phase Reactor with Immobilized Hexacyanoferrate(III)

摘要

An FIA assembly provided with immobilized hexacyanoferrate(III) is proposed for the fluorimetric determination of noradrenaline hydrochloride. The oxidative reagent is immobilized by means of a strong anion-exchange resin. The FIA manifold is very simple and the calibration graph is linear over the range 0.5-75mgl-1 noradrenaline hydrochloride with an r.s.d of 0.88% (17 replicates) and a sample throughput of 84b-1. Foreign compounds such as NaCl, sucrose, lactose and sodium sulfate caused no significant errors. The procedure is applied to the determination of noradrenaline in a medicinal formulation.