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Association between genetic risk score for telomere length and risk of breast cancer

机译:端粒长度的遗传风险评分与乳腺癌风险之间的关联

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摘要

While leukocyte telomere length (TL) has been associated with breast cancer risk, limited information is available regarding the role of genetically-determined TL on breast cancer risk. We investigated whether aggregated TL-associated variants are associated with the risk of breast cancer in 2,865 breast cancer cases and 2,285 controls from the Shanghai Breast Cancer Genetics Study.
机译:虽然白细胞端粒长度(TL)与乳腺癌的风险有关,但有关遗传测定的TL在乳腺癌风险中的作用的信息有限。我们在上海乳腺癌遗传学研究中调查了2865例乳腺癌病例和2285例对照中,与TL相关的聚集变异是否与乳腺癌风险相关。

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