Anodic square-wave stripping voltammetric analysis of epinephrine using carbon fiber microelectrode

摘要

The behavior of epinephrine on a carbon fiber microelectrode (CFME) was studied with cyclic voltammetry and square-wave (SW) stripping voltammetry in order to find optimum conditions for its analysis using the CFME. An anodic stripping peak at about 0.20 V (vs. Ag/AgCl) was utilized. Under optimum conditions for anodic stripping (a pH value of 7.4, a deposition potential of -0.5 V, a deposition time of 90 s, a final potential of 0.8 V, a SW frequency of 20 Hz, a step potential of 5 mV, and an amplitude of 45 mV), the calibration was linear in the concentration range of 0.00.4 mg/L, and the detection limit was found to be 0.009 mg/L with a relative standard deviation 0.18% (n= 12) at 0.2 mg/L. The analytical performance of the CMFE, which is unmodified, is comparable to or better than other voltammetric results with various modified electrodes. (c) 2006 Elsevier B.V. All rights reserved.