Hepatic NPC1L1 Overexpression Ameliorates Glucose Metabolism in Diabetic Mice Via Suppression of Gluconeogenesis

摘要

Objective. Inhibition of intestinal NPC1L1 by ezetimibe has been demonstrated to improve glucose metabolism in rodent models; however, the role of hepatic NPC1L1 in glucose metabolism has not been elucidated. In this study, we analyzed the effects of hepatic NPC1L1 on glucose metabolism.