Up-to-date opinions concerning immunoprophylaxis of mycoplasmal pneumonia in swine

摘要

The role of Mycoplasma (M.) hyopneumoniae in the pathogenesis of mycoplasmal pneumonia in swine (MPS), its importance in causing losses in swine production and the efficacy of specific bacterins in their reduction were described. The value of immunoprophylaxis in comparison to other procedures applied in the control of the disease was estimated. Cell-mediated immunity and mucosal immunity involving IgA located in the mucus of the bronchi were judged as important for protection against the disease. However, bacterins provide only partial protection and do not prevent the colonization and carriership of M. hyopneumoniae in the lungs. Research on new vaccines, including aerosol and feed-based vaccines, as well as subunit and DNA preparations were characterized. Finally, it was concluded that the application of vaccines in the control of MPS should be evaluated as a supplementary, economically acceptable method when combined with optimal herd management practices and housing conditions.