Selected endocrine tumors in animals: a review of cases in the years 1996-2007

摘要

The aim of the study was to estimate the prevalence and localization of different type of endocrine tumors in domestic animals in relation to age, sex and the breed of animals. The tissue specimens obtained during surgical procedures and necropsy materials were submitted to the Division of Pathomorphology, Faculty of Veterinary Medicine, Department of Clinical Sciences, Warsaw University of Life Sciences - WULS, from 1996-2007, for histopathological examinations. The tissue samples for histopathology were fixed in 10% buffered formalin, embedded in paraffin, 4 gm-thick sections were stained with haematoxylin and eosin method or others if needed. A total of 97 tumors were evaluated in this retrospective study. Most cases of endocrine tumors were found in dogs (84.5%), less in cats (8.2%), horses, domestic ferrets, goats (2.1% each species) and rats (1.0%). Over 60% of endocrine tumors were localized in the thyroid gland, especially in dogs (91.5% of all thyroid tumors), then in cats, more seldom in horses. They were prevalent in old age and were observed in both sexes. The breed prevalences of canine thyroid tumors were noted in dachshunds (20.4%). Adrenal gland (39.2%) were the second most frequent endocrine tumors predilection site. Adrenal gland tumors often appeared in dogs (34.1% of all canine endocrine tumors), rarely in cats, then in domestic ferrets, goats, rats. Malignant endocrine neoplasms were noted in 62.9% of the cases. More often malignant epithelial neoplasms were found in the thyroid. The majority of nonmalignant epithelial neoplasms (adenomas) were localized in adrenal glands. It is also worth noting rare cases animal tumors: thyroid oncocytoma and medullary thyroid carcinoma.