Splenomegaly in dogs: a survey of 97 cases.

摘要

The aim of the study was to estimate the prevalence of splenic diseases in dogs. 97 samples of spleen tissues and spleen tumours were obtained during laparotomy in veterinary clinics and sent for histopathological evaluation. The medical records were reviewed for sex, breed and age of animals and type of stated splenomegaly (diffuse or nodular). The tissue samples for histopathology were fixed in 10% buffered formalin, embedded in paraffin, sectioned at 5-6 micro m, and stained with haematoxylin-eosin method or other dyes. Primary and metastatic tumours of the spleen were the most commonly determined pathology (57% splenic lesions), nonneoplastic ones were more seldom observed. The most common type of splenic tumour was haemangiosarcoma (40% of splenic neoplasms), followed by spindle cellular sarcomas (24%), lymphomas (16%), and a few haemangiomas and metastatic tumours. Haemangiosarcomas were observed most commonly in male German shepherd dogs at 10 years of age. The majority of nonneoplastic lesions determined were diffuse or local circulatory disturbances and haematomas, while hyperplastic changes were rarely observed. The association between type of splenomegaly and kind of splenic lesions was not determined, but the nodular splenomegaly was more frequently observed in cases of haematomas and neoplasms of endothelial origin..