Immune response of foxes after vaccination with an attenuated vaccine against parvovirosis of dogs.

摘要

The objective of this study was to determine the level of antibodies in the sera of 2 groups of breeding foxes immunized with an attenuated vaccine against the parvovirus of dogs. Group I consisted of 40 female polar foxes divided into 4 subgroups based on the dose and route of vaccination. In group II, one variant of the vaccine was applied to 350 polar and silver foxes of both sexes. Blood was obtained in both groups before vaccination, 6 times in group I and once in group II. The level of antibodies was measured by the haemagglutinin inhibition (HI) and seroneutralization tests (SN). The HI and SN antibodies appeared in the sera 7 days after the vaccination. Their level significantly increased and peaked at the 21st day after vaccination. A high immunogenic value of the utilized vaccine was discovered. In antisera treated with kaolin, the level of HI antibodies decreased at least 4 times. The level of HI antibodies in sera absorbed with pig erythrocytes was accepted as reliable..