Comparative Study of the Antibacterial and Cytotoxicity of the Essential Oils from the Leaves, Stem Bark and Roots of Blighia unijugata Baker (Sapindaceae)

摘要

The antimicrobial activity of the essential oils (EOs) from Blighia unijugata Baker (Sapindaceae) was studied. EO was extracted from the leaves (BUL), stem bark (BUB) and roots (BUR) by hydrodistillation. These were all colorless and soluble in waterexcept for BUB. The EOs were active against Proteus mirabilis, Salmonella typhi, Escherichia coli, Bacillus subtilis and Pseudomonas mallei. BUB EO had the highest inhibitory zone (40 mm) against E. coli. BUB was also active against all the tested organisms except for P. fluorescens. All the EOs exhibited significant inhibitory activity against the pathogenic microorganisms. They all showed potent cytotoxicity with an LC_(50) of 85.20 mu g/ml (BUL), 70.50 mu g/ml (BUR) and 155.10 mu g/ml (BUB), which suggests an ethnomedicinal application of these EOs.