Radiochromic film dosimetry of a high dose rate beta source for intravascular brachytherapy.

摘要

Good clinical physics practice requires that dose rates of brachytherapy sources be checked by the institution using them, as recommended by American Association of Physicists in Medicine Task Group 56 and The American College of Radiology. For intravascular brachytherapy with catheter-based systems, AAPM Task Group 60 recommends that the dose rate be measured at a reference point located at a radial distance of 2 mm from the center of the catheter axis. AAPM Task Group 60 also recommends that the dose rate along the catheter axis at a radial distance of 2 mm should be uniform to within +/- 10% in the center two-thirds of the treated length, and the relative dose rate in the plane perpendicular to the catheter axis through the center of the source should be measured at distances from 0.5 mm to R90 (the distance from a point source within which 90% of the energy is deposited) at intervals of 0.5 mm. Radiochromic film dosimetry has been used to measure the dose distribution in a plane parallel to and at a radial distance of 2 mm from the axis of a novel, catheter-based, beta source for intravascular brachytherapy. The dose rate was averaged along a line parallel to the catheter axis at a radial distance of 2 mm, in the centered 24.5 mm of the treated length. This average dose rate agreed with the dose rate measured with a well ionization chamber by the replacement method using source trains calibrated with an extrapolation chamber at the National Institute of Standards and Technology. All of the dose rates in the centered 24.5 mm of a line parallel to the axis at a distance of 2 mm were within +/-10% of the average.