Correlation of FMISO simulations with pimonidazole-stained tumor xenografts: A question of O-2 consumption?

摘要

Purpose: To compare a dedicated simulation model for hypoxia PET against tumor microsections stained for different parameters of the tumor microenvironment. The model can readily be adapted to a variety of conditions, such as different human head and neck squamous cell carcinoma (HNSCC) xenograft tumors.