A 23.4 KB SEGMENT AT THE 69-DEGREES-70-DEGREES REGION OF THE BACILLUS SUBTILIS GENOME

摘要

Within the framework of the international project aimed at the sequencing of the Bacillus subtilis genome, a 23.4 kb chromosome segment has been cloned and sequenced. This region (23433 bp; 69 degrees-70 degrees of the genetic map) contains 17 complete ORFs and a partial one. A homology search for the products deduced from the 18 ORFs revealed that twelve of them had significant similarity to known proteins, including the quinolone-resistance protein, ABC transporter, aldehyde dehydrogenase, amino acid transporter, fosmidomycin-resistance protein, CDP-glucose 4,6-dehydratase, glucose-1-phosphate cytidyltransferase and cytochrome P450/NADPH-cytochrome P450 reductase.