Hepatoblastoma and low birth weight: a trend or chance observation?

摘要

BACKGROUND: Several reports have suggested an association between prematurity and hepatoblastoma (HB). PROCEDURE: Data were collected by questionnaires from 105 children with HB enrolled in a Children's Cancer Group (CCG) study. RESULTS: Observed over expected rates were increased about 2- and 15+-fold for prematurity (<37 weeks at birth) and low birth weight (<1,000 g) respectively. Similar data were derived from a later CCG study of 36 HB children. CONCLUSIONS: Early reports of a possible association between prematurity and HB have been confirmed. Copyright 2002 Wiley-Liss, Inc.