The effect of low level laser (GaAlAs) therapy on the post-surgical healing of full thickness wounds in rabbits

摘要

Objective: Our purpose was to determine the efficacy of low level laser therapy (LLLT) on wound healing in rabbits. Study design: Sixteen rabbits were sedated and given a general anesthetic. A full thickness flap was used bilaterally at the buccal gingiva maxilla in a naturally toothless area, and then sutured. A low level pulsed GaAlAs laser (wavelength: 685 nm, power: 45 mW, radiant exposure: 3 J/cm~2, frequency: 10 Hz, duty factor: 80%; application time: 1 min) was used on the left side. The right side was not lasered as a control. Tissue specimens from each site on days 3, 7, and 14 after surgery were examined microscopically. Results: Less inflammation was observed on days 3 and 7 in the treatment group (p < 0.01). The inflammation rate on both sides was the same on day 14 (p > 0.05). Conclusion: LLLT using optimal parameters can accelerate full thickness wound healing.