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An Open Innovation Decision Support System to Select a Biopharmaceutical R&D Portfolio

机译:选择生物制药研发项目的开放式创新决策支持系统

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摘要

Drugs available in the market today, selected several years ago under very uncertain future scenario, have experienced a long and expensive process of research and development carried out following both a closed and an open innovation path. To support this critical selection process, we propose a Decision Support System, able to choose among different candidates the most promising drugs along their best development path. The Decision Support System, based on a real options portfolio optimization model, mapping tools, and what-if rules as well, has been applied to a numerical example available in literature, and the research findings show interesting managerial and academic implications.
机译:几年前在非常不确定的未来情况下选择的当今市场上可用的药物,经历了封闭和开放的创新路径,进行了漫长而昂贵的研发过程。为了支持这一关键的选择过程,我们提出了决策支持系统,该系统能够在不同的候选人中选择沿其最佳发展道路最有希望的药物。基于实物期权投资组合优化模型,映射工具和假设假设规则的决策支持系统已应用于文献中的数字示例,研究结果显示出有趣的管理和学术意义。

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