Is there a role of pancreatic steatosis together with hypertrigliceridemia on the pathogenesis of diabetes in a patient with type 2 diabetes mellitus?

摘要

It is well known that hyperinsulinemia, related to peripheric insulin resistance, and loss of glucose stimulated insulin secretion, or both of them are responsible for pathogenesis of type 2 diabetes mel-Utus (DM). We hypothesized that pancreatic steatosis related with hypertrigliceridemia may play an important role in pathogenesis of type 2 DM.A 54 year old woman applied to our clinic with complaints of polyuria, polydipsia, weight loss, fatigue and weakness for one month. Physical examination indicated dehydratation and tenderness in the epigastric and left upper abdominal quadrant.