Total assignment of H-1 and C-13 spectra of the chlorinated triterpenoid (methyl 2 alpha,3 beta,24-tri-O-acetylolean-12 alpha-chloro-28,13 beta-olide) by NMR spectroscopy

摘要

The current substantial interest concerning the structure elucidation of new active natural products led to the complete H-1 and C-13 chemical shift assignment of a triterpenoid derivative, methyl 2 alpha,3 beta,24-tri-O-acetylolean-12 alpha-chloro-28,13 beta-olide, obtained after acetylation and methylation of a mixture isolated from Mentha villosa. The 2D shift-correlated NMR techniques HMBC, HMQC, COSY and NOESY were used. (C) 1998 John Wiley & Sons, Ltd. [References: 9]