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首页> 外文期刊>Macromolecular symposia >Evaluation of Chitosan/Biphasic Calcium Phosphate Scaffolds for Maxillofacial Bone Tissue Engineering
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Evaluation of Chitosan/Biphasic Calcium Phosphate Scaffolds for Maxillofacial Bone Tissue Engineering

机译:壳聚糖/双相磷酸钙支架在颌面骨组织工程中的评价

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摘要

Porous, 3D chitosan/biphasic calcium phosphate (BCP) scaffolds were usedto prepare tissue engineering constructs for maxillofacial bone tissue reconstruction.Mesenchymal stem cells (MSC's) were seeded and cultured on clinically relevant sizedscaffolds. In vitro engineered constructs facilitated the healing of mandibular defectsin pigs if accompanied with delivery of basic fibroblast growth factor (bFGF).
机译:使用多孔的3D壳聚糖/双相磷酸钙(BCP)支架来制备用于颌面骨组织重建的组织工程构建体。将间充质干细胞(MSC's)播种并在临床相关大小的支架上进行培养。如果伴有碱性成纤维细胞生长因子(bFGF)的递送,体外工程化的构建体可促进猪下颌骨缺损的愈合。

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