Schizophrenia halted by PAK inhibitor

摘要

Scientists based at Johns Hopkins University School of Medicine (MD, USA) have discovered that an experimental cancer drug, FRAX486, appears to reverse schizophrenia-associated behavior and restore some of the lost neuron communication in adolescent mice. FRAX486 is part of the PAK inhibitor class of compounds; this class of inhibitors has previously been tested against Alzheimer's disease and cancer.