Thromboelastographic~R monitoring of the efficacy of recombinant factor Vila administration in a parturient with factor VII deficiency

摘要

A 35-yr-old parturient with factor VII deficiency presented at term with a factor VII level of less than 3%. Coagulation studies revealed a prothrombin time (PT) of 32.3 sec, international normalized ratio (INR) of 3.2, partial thromboplastin time (PIT) of 30.3 sec and hematocrit (Hct) of 37.2%. Two units of fresh frozen plasma (FFP) were transfused prior to epidural placement. A follow-up set of coagulation studies revealed a PT of 22.9 sec, INR of 2.0 and PTT of 30.3 sec.