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Poetry is in the air: First multi-institutional results of the per-oral endoscopic myotomy procedure for achalasia

机译:诗意盎然:经口内窥镜肌切开术治疗门失弛缓症的第一个多机构研究结果

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摘要

So what is there not to like about POEM? It is as fast to perform as a laparoscopic Heller, with better early results than a Heller myotomy, balloon dilation, or Botox, and a recovery typical of a surgical or endoscopic treatments. In short: Surgical efficacy with the recovery profile of an endoscopy. Certainly 1 issue of concern is the decrease in efficacy noted over the course of the first year in this registry experience—from 97% at 3 months to 83% at 12 months—a somewhat worrisome trend. One suspects that this may be a factor of the multicenter nature of this study, where some centers had relatively little prior exposure to the procedure. In fact, this late recurrence phenomenon has not been reported in the larger, single-center series published to date, several with follow-up of 2-3 years.
机译:那么,POEM有什么不受欢迎的呢?它的执行速度与腹腔镜Heller一样快,并且比Heller肌切开术,球囊扩张术或肉毒杆菌毒素具有更好的早期结果,并且具有手术或内窥镜治疗的典型恢复能力。简而言之:具有内窥镜检查恢复特征的手术疗效。当然,值得关注的一个问题是,在该注册管理机构经验的第一年中,功效下降了,从3个月的97%下降到12个月的83%,这是一个令人担忧的趋势。一个人怀疑这可能是这项研究的多中心性质的一个因素,在该研究中,某些中心以前很少接触该程序。实际上,迄今已发表的较大的单中心研究尚未报道这种晚期复发现象,其中一些随访时间为2-3年。

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