Proteome analysis: a new approach to identify key proteins involved in acquisition of maturational competence and oocyte maturation of medaka oocytes

摘要

We have applied analytical methods of proteomics to identify key proteins that are involved in physiologically important processes on fish reproduction. We have improved methods of proteome analysis for fish oocytes and revealed changes of expression patterns of oocyte proteins and protein phosphorylation during acquisition of maturational competence and signal transduction of oocyte maturation of medaka oocytes.