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首页> 外文期刊>Fish Physiology and Biochemistry >Existence of a nitric oxide synthaseitric oxide system in fish testis and its role in modulation of androgenesis.
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Existence of a nitric oxide synthaseitric oxide system in fish testis and its role in modulation of androgenesis.

机译:鱼睾丸中一氧化氮合酶/一氧化氮系统的存在及其在雄激素生成中的作用。

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摘要

Fish testis is equipped with different isoforms of nitric oxide synthase (NOSs) and is capable of producing nitric oxide (NO). Cellular sources of NO in the catfish testis are germ cells, Leydig cells, and macrophages. Production of testicular NO is under endocrine inhibitory control. Expression of NOSs exhibits seasonality and that depends on the reproductive status of fish. Leydig cells are highly sensitive to chemical as well as biological NO. NO inhibits testosterone production by the testis in vivo as well as by the isolated Leydig cells in vitro.
机译:鱼睾丸装有一氧化氮合酶(NOS)的不同同工型,并且能够产生一氧化氮(NO)。 the鱼睾丸中NO的细胞来源是生殖细胞,Leydig细胞和巨噬细胞。睾丸NO的产生受内分泌抑制控制。 NOS的表达具有季节性,这取决于鱼的繁殖状况。 Leydig细胞对化学以及生物NO高度敏感。 NO抑制体内睾丸以及体外分离的Leydig细胞产生睾丸激素。

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