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A review of silicon and silicone determination in tissue and body fluids - a need for standard reference materials

机译:综述组织和体液中硅和硅的测定-对标准参考物质的需求

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摘要

The role of Si in nature is briefly described, especially the toxic properties of inorganic and organic Si for humans. The use of different forms of silicones in medicine and food industry is noted and potential consequences of their use are discussed. Since Si is an essential trace element there is need for establishment of the "normal" level of Si in blood, other body fluids and tissues and development of speciation of Si forms in biological samples. Numerous difficulties in the determination of Si are described and the need for SRM is stressed. The results of the determination of Si in blood of patients with Si breast implants and controls, Si in milk and blood of nursing mothers - with and without Si boast implants and extractable Si in capsules - are summarized. The obtained data reinforce the need for a reliable SRM. [References: 30]
机译:简要描述了硅在自然界中的作用,尤其是无机和有机硅对人类的毒性。指出了在医药和食品工业中使用不同形式的有机硅,并讨论了其使用的潜在后果。由于硅是必需的微量元素,因此需要在血液,其他体液和组织中建立硅的“正常”水平,并发展生物样品中硅形态的形成。描述了确定硅的许多困难,并强调了对SRM的需求。总结了含硅丰胸植入物和对照的患者的Si乳房植入物和对照患者血液中Si的测定结果,有或没有Si吹嘘植入物和胶囊中可萃取Si的哺乳母亲的牛奶和血液中Si的测定结果。获得的数据加强了对可靠SRM的需求。 [参考:30]

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