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Current applications of biomarkers in cardiomyopathies.

机译:生物标志物在心肌病中的当前应用。

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摘要

Cardiomyopathies are an important cause of sudden cardiac death in young people and are responsible for arrhythmias and premature heart failure in all age groups. Although many cardiomyopathies are inherited, biochemical markers are a fundamental part of the diagnostic work-up and are useful in the prognostic assessment of disease. In this article, the authors review the rationale and evidence for important biomarkers according to their role in patient management. Emerging biomarkers are briefly reviewed, alongside modern scientific approaches to biomarker discovery.
机译:心肌病是年轻人心源性猝死的重要原因,是所有年龄段的心律不齐和早衰的原因。尽管许多心肌病是遗传性的,但生化标志物是诊断工作的基本组成部分,可用于疾病的预后评估。在本文中,作者根据重要生物标志物在患者管理中的作用,回顾了其原理和证据。简要回顾了新兴的生物标记,并结合了现代的生物标记发现科学方法。

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