Radiotherapy (RT) is an extremely effective treatment for head and neck cancer, both as a primary modality and as an adjuvant treatment following surgery. RT causes significant acute (during and up to 3 months postradiation) and late toxicity when used at doses required to sterilize the locoregional disease (radical doses). The acute toxicities include mucositis, dysphagia, xerostomia, dermatitis and pain. Radiation-induced mucositis of the upper aerodigestive tract results in significant morbidity and altered quality of life (QoL) during RT
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