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首页> 外文期刊>Forensic science international. Genetics >Population and forensic data for three sets of forensic genetic markers in four ethnic groups from Iran: Persians, Lurs, Kurds and Azeris
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Population and forensic data for three sets of forensic genetic markers in four ethnic groups from Iran: Persians, Lurs, Kurds and Azeris

机译:来自伊朗四个民族的三个法医遗传标记物的人口和法医数据:波斯人,卢尔斯,库尔德人和阿塞拜疆人

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A total of 255 individuals (Persians, Lurs, Kurds and Azeris) from Iran were typed for three sets of forensic genetic markers with the NGM SElect (TM), DIPplex (R) and Argus X-12 kits. Statistically significant deviations (P <= 0.002) from Hardy-Weinberg expectations were observed for the insertion-deletion markers HLD97 and HLD93 after Holm-Sidak correction. Statistically significant (P < 0.05) levels of linkage disequilibrium were observed between markers within two of the four studied X-chromosomal linkage groups. AMOVA analyses of the three sets of markers did not show population structure when the individuals were grouped according to their ethnic group. The Iranian population grouped closely to populations living geographically near to Iran based on pairwise F-ST distances. The matching probabilities ranged from 1 in 3.2 x 10(7) males by using haplotype frequencies of four X-chromosomal haplogroups to 1 in 3.4 x 10(21) individuals for the 16 autosomal STRs. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
机译:使用NGM SElect(TM),DIPplex(R)和Argus X-12试剂盒对来自伊朗的总共255个人(波斯人,卢尔斯,库尔德人和阿塞拜疆人)进行了三组法医遗传标记的分类。在Holm-Sidak校正后,对于插入缺失标记HLD97和HLD93,观察到与Hardy-Weinberg期望有统计学差异(P <= 0.002)。在四个研究的X染色体连锁组中的两个之间的标记之间观察到连锁不平衡的统计学显着水平(P <0.05)。当根据种族将个体分组时,对这三组标记的AMOVA分析未显示人口结构。基于成对的F-ST距离,伊朗人口与居住在地理上靠近伊朗的人口紧密分组。通过使用四个X染色体单倍群的单倍型频率,匹配概率的范围从3.2 x 10(7)个男性中的1个到16个常染色体STR的3.4 x 10(21)个个体中的1个。 (C)2015 Elsevier Ireland Ltd.保留所有权利。

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