Regression of soft drusen and drusenoid pigment epithelial detachment following intravitreal anti-vascular endothelial growth factor therapy.

摘要

Drusenoid pigment epithelial detachment (PED), defined as half a disc diameter or greater of confluent drusen under the central macula, and soft confluent macular drusen are considered a precursor to choroidal neovascularization (CNV). Treatment of soft confluent drusen has been attempted in the hope that this may reduce the risk of CNV. Argon laser photocoagulation showed a significant decrease in drusen in treated eyes but no significant CNV reduction