Synthesis of regioisomeric (S)-(+)-3,3,4-trimethyl-8-methoxy-3,4-dihydrobenzoh-isoquinolin-l(2H)-one and (S)-(+)-1,2,2-trimethyl-8-methoxy-1,2-dihydrobenzof-isoquinolin-4(3H)-one by the Ritter reaction

摘要

The conservation of chirality at the alpha-position to the carbocationic centre of (S)-(-)-2-methyl-3-(6-methoxynaphth-2-yl)butan-2-ol and the formation of regioisomeric (S)-(+)-1,2,2-trimethyl-8-methoxy-1,2-dihydrobenzofisoquinolin-4(3H)-one were found in the synthesis of (S)-(+)-3,3,4-trimethyl-8-methoxy-3,4-dihydrobenzohisoquinolin-1(2H)-one by the Ritter reaction.