Comment on ' toxic hepatitis in a group of 20 male body-builders taking dietary supplements' by Timcheh-Hariri et al. (2012)

摘要

In their recent publication in "Food Chem. Toxicol. July 15th 2012 (Timcheh-Hariri et al., 2012) on: "Toxic hepatitis in a group of 20 male body-builders taking dietary supplements", Timcheh-Hariri et al. report a dramatic picture of 20 body-builders presenting with toxic hepatitis after self-prescribing a number of "dietary supplements which are lesser known". The subjects ingested a total of three such supplements for a time period of one year. These were: first Phosphagen (Timcheh-Hariri et al. Fig. 1) containing pure cre-atine-monohydrate, second a formulation called "T-BOMB" with 903 mg of an ingredient called "Optimone 5TM: Five Phase Hormone Optimizing Blend" as one of the main constituents, including some herbal extracts etc. (Fig. 2) and third a supplement with amino acids, a creatine-formulation, sugar, salts and vitamins, as well as an unspecified product called "Insulo Drive!" (Fig. 3). No information is given on any daily dose level of either of these supplements neither on other nutritional or behavioral habits of the body builders.