Comment on ' Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize' by Séralini et al.

摘要

On 19 September 2012, Seralini et al. published online in this journal the results of a long term toxicity study that, in their opinion, revealed clear indications that genetically modified NK603 maize and Roundup are dangerous to health. VIB has reviewed the Seralini et al. paper in detail (VIB, 2012) and in this comment, we point out the most critical flaws in Seralini's design, interpretation and reporting. Because of these fundamental flaws, the conclusions of Seralini et al. are not substantiated in any way.Seralini et al. fed rats during a period of two years with either NK603 maize (three different doses: 11%; 22% or 33%), with NK603 maize (the same three different doses) that was sprayed with Roundup, or provided drinking water in which Roundup was present (three different concentrations: 50 ng/1, 400 mg/1 or 2.25 g/1). In this way nine different treatments were tested and were compared with only one negative control, being a diet with one dose (i.e. 33%) of near-isogenic non-GM maize. Each diet was fed to 10 male and 10 female rats, which means that in total 200 rats were tested.