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Triterpenoids from Calophyllum inophyllum and their growth inhibitory effects on human leukemia HL-60 cells

机译:茶树中的三萜类化合物及其对人白血病HL-60细胞的生长抑制作用

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摘要

A new friedelane-type triterpene (1), along with seven known triterpenoids, was isolated from the stems and leaves of Calophyllum inophyllum Linn. Their structures were established as 3 beta, 23-epoxy-friedelan-28-oic acid (1), friedelin (2), epifriedelanol (3), canophyllal (4), canophyllol (5), canophyllic acid (6), 3-oxo-friedelan-28-oic acid (7), and oleanolic acid (8) by spectroscopic methods (NMR, EI-MS). The growth inhibitory effects of these triterpenoids on human leukemia HL-60 cells were determined. Crown Copyright
机译:从Calophyllum inophyllum Linn的茎和叶中分离出一种新的Friedelane型三萜(1),以及7种已知的三萜。它们的结构被确定为3β,23-环氧-friedelan-28-oic酸(1),Friedelin(2),epifriedelanol(3),canophyllal(4),canophyllol(5),canophyllic acid(6),3-通过光谱法(NMR,EI-MS)测定氧代-弗里德兰-28-酸(7)和齐墩果酸(8)。确定了这些三萜类化合物对人白血病HL-60细胞的生长抑制作用。皇冠版权

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