Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia

摘要

Objective To analyze whether the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia. Design Case report. Setting In vitro fertilization unit of a public hospital. Patient(s) Thirty-one-year-old nulliparous woman, and 39-year-old male with retrograde ejaculation and absolute asthenozoospermia. Intervention(s) Retrieval of postejaculatory urine, restoration of motility using a methylxanthine, intracytoplasmic sperm injection, single-embryo transfer. Main Outcome Measure(s) Sperm motility, fertilization, embryo quality, live birth. Result(s) Successful fertilization and a single-embryo transfer resulted in a healthy live birth. Conclusion(s) Theophylline turned out to be a safe, efficient agent for stimulating immotile spermatozoa in patients with retrograde ejaculation.