Sperm proteomics: Fertility diagnostic testing beyond the semen analysis?

摘要

Proteome refers to the complement of proteins produced by an organism or biologic system (1). These proteins can change with time due to internal physiologic requirements or environmental stressors. Proteomics refers to the study of these protein changes to gain a better understanding of the underlying cellular processes within the organism or biologic system. The study by Pilatz et al. (2) provides a vision into sperm proteomics within an inflammatory environment caused by epididymitis.