c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study

Hussein Mostafa; Chai Daniel C.; Kyama Cleophas M.; Mwenda Jason M.; Palmer Stephen S.; Gotteland Jean-Pierre; DHooghe Thomas M.

首页> 外文期刊>Fertility and Sterility: Official Journal of the American Fertility Society, Pacific Coast Fertility Society, and the Canadian Fertility and Andrology Society >c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study

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c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study

机译：c-Jun NH2末端激酶抑制剂Bentamapimod减少狒狒诱发的子宫内膜异位：评估者-盲目安慰剂对照的随机研究

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摘要

Objective: To test the hypothesis that the c-Jun NH2-terminal kinase (JNK) inhibitor (JNKI) bentamapimod (AS602801/PGL5001) can reduce induced endometriosis in baboons.

机译：目的：检验以下假设：c-Jun NH2末端激酶（JNK）抑制剂（JNKI）苯达莫德（AS602801 / PGL5001）可以减少狒狒的内异症。

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《Fertility and Sterility: Official Journal of the American Fertility Society, Pacific Coast Fertility Society, and the Canadian Fertility and Andrology Society》 |2016年第3期|共15页
作者
Hussein Mostafa; Chai Daniel C.; Kyama Cleophas M.; Mwenda Jason M.; Palmer Stephen S.; Gotteland Jean-Pierre; DHooghe Thomas M.;
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正文语种 eng
中图分类妇科学;
关键词
JNK; endometriosis; baboons; endometriotic lesions; biomarkers;

机译：JNK;子宫内膜异位症;狒狒;子宫内膜异位病变;生物标志物;

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1. c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study [J] . Hussein Mostafa, Chai Daniel C., Kyama Cleophas M., Fertility and Sterility: Official Journal of the American Fertility Society, Pacific Coast Fertility Society, and the Canadian Fertility and Andrology Society . 2016,第3期

机译：c-Jun NH2末端激酶抑制剂Bentamapimod减少狒狒诱发的子宫内膜异位：评估者-盲目安慰剂对照的随机研究
2. A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo. [J] . Milano G, Morel S, Bonny C, American Journal of Physiology . 2007,第4期

机译：c-Jun NH2末端激酶的肽抑制剂可减少体内心肌缺血-再灌注损伤和梗塞面积。
3. A peptide inhibitor of c-Jun NH2-terminal kinase reduces myocardial ischemia-reperfusion injury and infarct size in vivo. [J] . Milano G, Morel S, Bonny C, American Journal of Physiology . 2007,第4期

机译：c-Jun NH2末端激酶的肽抑制剂可减少体内心肌缺血-再灌注损伤和梗塞面积。
4. MULTI-CENTER, PLACEBO-CONTROLLED, DOUBLE-BLIND, RANDOMIZED STUDY OF ORAL TOCERANIB PHOSPHATE (PALLADIATM, SU11654), A RECEPTOR TYROSINE KINASE INHIBITOR, FOR THE TREATMENT OF DOGS WITH RECURRENT MAS [C] . Cheryl L London, Carolyn J Henry, Anthony W Rusk, Annual conference of the Veterinary Cancer Society . 2008

机译：多中心，安慰剂对照，双盲，随机研究口服Toceranib磷酸盐（Palladia TM，SU11654），受体酪氨酸激酶抑制剂，用于治疗经常性MAS的狗
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. AS601245 a c-Jun NH2-terminal kinase (JNK) inhibitor reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils [O] . S Carboni, U Boschert, P Gaillard, 2008

机译：AS601245一种c-Jun NH2末端激酶（JNK）抑制剂可降低沙鼠全脑缺血后的轴突/树突损伤和认知缺陷
7. c-Jun NH 2 -terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study [O] . Mostafa Hussein, Daniel C. Chai, Cleophas M. Kyama, 2016

机译：C-Jun NH 2 -Terminal激酶抑制剂Bentamapimod减少了狒狒中的诱发子宫内膜异位症：评估率 - 盲人安慰剂对照随机研究

c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study

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