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The artificial ovary: Any new step is a step forward

机译:人工卵巢:任何新的步骤都是前进的一步

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摘要

Several advances have come about during the last decade in the field of fertility preservation. Cryopreservation of ovarian cortex and transplantation (COC-T) is probably the most relevant technique for patients who are not eligible to undergo oocyte or embryo vitrification. This procedure minimizes time lapses before oncologic treatments and allows the preservation of fertility in young prepubertal girls for whom controlled ovarian stimulation is not a valid option. Unfortunately, COC-T is not safe when there is an increased risk of reintroduc-ing malignant cells, such as Burkitt's lymphoma or leukemia (1). At present, there is no clinical alternative for these kinds of patients to preserve their fertility, although there are several experimental approaches that aim to provide safe options.
机译:在过去的十年中,在生育保护领域取得了一些进展。对于没有资格进行卵母细胞或胚胎玻璃化治疗的患者,卵巢皮质的冷冻保存和移植(COC-T)可能是最相关的技术。该程序可最大程度地减少肿瘤治疗之前的时间流逝,并能保持青春期前的青春期女孩的生育能力,因为对于这些女孩而言,有效的卵巢刺激是无效的。不幸的是,当重新引入恶性细胞(例如伯基特氏淋巴瘤或白血病)的风险增加时,COC-T是不安全的(1)。目前,尽管有几种旨在提供安全选择的实验方法,但对于这类患者而言,没有其他替代方法可以保持他们的生育能力。

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