Synthesis of some N-4-(benzothiazole-2yl) phenyl-2-aryloxyacetamide derivatives and their anticancer activities

TayF.; Yurtta?L.; DemirayakS.

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Synthesis of some N-4-(benzothiazole-2yl) phenyl-2-aryloxyacetamide derivatives and their anticancer activities

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In this study, some N-4-(Benzothiazole-2-yl) phenyl-2-aryloxyacetamide derivatives were prepared by reacting N-4-(benzothiazole-2yl)phenyl-2- chloroacetamide and different substituent phenol or thiophenol derivatives. The anticancer activities of the compounds obtained were investigated. It was observed that some of the compounds, namely 25 and 38, showed notable anticancer activity.

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《Journal of enzyme inhibition and medicinal chemistry》 |2012年第4期|515-520|共6页
作者
TayF.; Yurtta?L.; DemirayakS.;
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作者单位

Department of Chemistry, Faculty of Arts and Sciences, Eskisehir Osmangazi University, 26480;

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkey;

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medipol University, Istanbul, Turkey;

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原文格式 PDF
正文语种英语
中图分类酶;
关键词
Antitumour; Benzothiazole; Non-small cell lung cancer; Prostate cancer;

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Synthesis of some N-4-(benzothiazole-2yl) phenyl-2-aryloxyacetamide derivatives and their anticancer activities

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