Biochemical markers of oxidative stress and retinopathy of prematurity.

摘要

We read with interest the article by Perrone et al. regarding the association of free-radical related diseases (FRDs) and biochemical markers of oxidative stress (OS) in infantile cord blood [1 ], testing the hypothesis that the levels of OS markers in cord blood might predict the onset of FRDs including retinopathy of prematurity (ROP). The authors noted that this study was of inadequate power to define the relative increase risk for each FRD, although globally the risk was increased with elevated cord blood levels of OS markers.