S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression

Cheng Gumeng; Tian Kailin; Zhang Lu; Yang Ning; Xing Yiqiao; He Tao

首页> 外文期刊>Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie >S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression

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S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression

机译：S100A4基因沉默在氧诱导的缺血性视网膜病中通过下调CREB表达抑制视网膜新血管形成

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Purpose To investigate the possible role of S100A4 in retinal neovascularization (RNV), as well as the underlying mechanism, in a mouse model of oxygen-induced retinopathy (OIR).

机译：目的研究S100A4在氧诱导性视网膜病变（OIR）小鼠模型中在视网膜新血管形成（RNV）中的可能作用及其潜在机制。

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《Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie》 |2016年第1期|共12页
作者
Cheng Gumeng; Tian Kailin; Zhang Lu; Yang Ning; Xing Yiqiao; He Tao;
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正文语种 eng
中图分类眼科学;
关键词
Retinal neovascularization; Oxygen-induced retinopathy; Adenovirus-mediated RNAi transfer; S100A4; cAMP response element-binding protein;

机译：视网膜新血管形成;氧致视网膜病;腺病毒介导的RNAi转移;S100A4;cAMP反应元件结合蛋白;

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1. S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression [J] . Cheng Gumeng, Tian Kailin, Zhang Lu, Graefe's archive for clinical and experimental ophthalmology: Albrecht von Graefes Archiv fur klinische und experimentelle Opthalmologie . 2016,第1期

机译：S100A4基因沉默在氧诱导的缺血性视网膜病中通过下调CREB表达抑制视网膜新血管形成
2. Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy [J] . Yang Ning, Zhang Wenxi, He Tao, Experimental Eye Research . 2017,第期

机译：Galectin-1的沉默抑制视网膜新生血管和改善氧气诱导的缺血性视网膜病变的小鼠模型中的视网膜缺氧
3. Overexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression [J] . Chen Zhen, Du Ke, He Tao, Molecular vision . 2012,第2012期

机译：氧诱导的缺血性视网膜病中15-脂氧合酶-1的过表达通过下调血管内皮生长因子-A的表达抑制视网膜新血管形成
4. Fractal analysis of neovascularization due to diabetic retinopathy in retinal fundus images [C] . Sathvika Mudigonda, Faraz Oloumi, Kalyana M. Katta, IEEE International Conference on E-Health and Bioengineering . 2015

机译：糖尿病性视网膜病在视网膜眼底图像中新生血管形成的分形分析
5. Novel mechanisms for the involvement of hypercapnia in retinal blood flow and neovascularization: Implications for retinopathy of prematurity and beyond. [D] . Checchin, Daniella Marie. 2006

机译：高碳酸血症参与视网膜血流和新生血管形成的新机制：对早产儿及以后的视网膜病变的影响。
6. Silencing of S100A4 a metastasis-associated protein inhibits retinal neovascularization via the downregulation of BDNF in oxygen-induced ischaemic retinopathy [O] . G Cheng, T He, Y Xing 2016

机译：沉默S100A4一种转移相关蛋白通过下调BDNF在氧诱导的缺血性视网膜病变中抑制视网膜新生血管形成
7. Silencing of S100A4, a metastasis-associated protein, inhibits retinal neovascularization via the downregulation of BDNF in oxygen-induced ischaemic retinopathy [O] . G Cheng, T He, Y Xing 2016

机译：S100A4的沉默，转移相关蛋白质，通过在氧气诱导的缺血性视网膜病变中的BDNF的下调来抑制视网膜新生血管

S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression

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