The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations.

摘要

Sir, We read with great interest the article entitled 'Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?' by Peyriere et al. Based on data collected retrospectively from the French Pharmacovigilance database, the authors concluded that the acronym 'DRESS' is both inaccurate and quite imprecise with no clear definition regarding both cutaneous and systemic signs. We believe, however, that many of the authors' considerations are in contrast to the current knowledge about this syndrome and may be based on misinterpretations of these data probably due to their unawareness of several important findings uniquely observed in this syndrome.