Pigmented squamous cell carcinoma of the nail bed presenting as a melanonychia striata: Diagnosis by perioperative reflectance confocal microscopy

摘要

Madam, Although dermoscopy has allowed the determination of an algorithm for the evaluation and management of mel-anonychia striata (MS), such lesions remain a diagnostic challenge in ambiguous cases.1'2 We recently showed in a series of eight subungual melanomas and a lentigo that perioperative reflectance confocal microscopy (RCM) could improve the diagnostic performance of dermoscopy, and enable, in typical cases, both the diagnosis and the treatment of an in situ or minimally invasive subungual melanoma within a one-step surgical procedure; this reduces the pain induced by repeated invasive surgical procedures on the nail apparatus, as well as the postoperative disability period.