Characterization of a malignant T-cell line established from a rare case of CD8+CD56+ Sézary syndrome

摘要

Madam, The majority of cell lines derived from mycosis fungoides and Sezary syndrome (SS), representatives of cutaneous T-cell lymphoma (CTCL), are positive for CD4, and CD8~+ cases are rare. Here, we established a CD8~+CDS6~+ skin-infiltrating tumour cell line from skin blisters of a patient with CD8~+ SS. Using this cell line, the peculiar features of CD8~+ CTCL cells were studied.