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外文期刊>Mendeleev Communications
>Synthesis of 5-oxo-4,5,6,7-tetrahydro-1H-pyrrolo-3,2-bpyridine-3- carboxylic acids by three-component condensation of 3-aminopyrrole derivatives
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Synthesis of 5-oxo-4,5,6,7-tetrahydro-1H-pyrrolo-3,2-bpyridine-3- carboxylic acids by three-component condensation of 3-aminopyrrole derivatives
5-Oxo-4,5,6,7-tetrahydro-1H-pyrrolo3,2-bpyridine-3-carboxylic acids were prepared by three-component condensation of 3-aminopyrroles, (het)aromatic aldehydes and Meldrum's acid. The labile intermediate 3-aminopyrrole derivative was generated in situ by regioselective (at 2-position) decarboxylation of 3-aminopyrrole-2,4-dicarboxylic acid.
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