Subcutaneous panniculitis-like T-cell lymphoma alphabeta: complete sustained remission with corticosteroids and methotrexate.

摘要

Madam, The subcutaneous panniculitis-like T-cell lymphoma (SPTL) was denned as a distinct entity by the World Health Organization (WHO) classification in 2005' and this definition was adopted by the WHO classification in 2008. In this classification the term 'SPTL' was used only for cases with a alphabeta T-cell phenotype whereas cases with a gammadelta T-cell phenotype were included in the category of cutaneous gammadelta T-cell lympho-mas that display a much more aggressive clinical course. ' Recent studies suggest that the disease course in patients with SPTL could be controlled for long periods of time with systemic corticosteroids instead of doxorubicin-based chemotherapies. We report four cases of patients with SPTL-oalphabeta treated with corticosteroids, methotrexate, or a combination of both treatments, who achieved a long-term complete remission.