首页> 外文期刊>British Journal of Clinical Pharmacology >Preferential prescribing of oral corticosteroids in Irish male asthmatic children.
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Preferential prescribing of oral corticosteroids in Irish male asthmatic children.

机译:爱尔兰男性哮喘儿童的口服糖皮质激素优惠处方。

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摘要

AIMS: To determine if there is a gender difference in the prescription of oral corticosteroids in asthmatic children (< 15 years). METHODS: 8072 asthmatics were identified on the basis that they received a prescription for either an inhaled beta-adrenoceptor agonist, an inhaled corticosteroid, inhaled cromoglycateedocromil sodium, oral xanthines or leukotriene antagonist. Odds ratios (OR) and 95% confidence intervals (CI) were determined for the different asthma treatments for males compared with females. RESULTS AND CONCLUSIONS: Male asthmatic children were more likely (OR = 1.37, 95% CI = 1.21,1.55, P < 0.001) to receive a prescription for an oral corticosteroid compared with their female counterparts suggesting a possible increased severity of their condition, rather than a different management of their disease. Male asthmatic children were less likely to be prescribed an antibiotic over the study period (OR = 0.85, 95% CI = 0.77, 0.93, P < 0.001).
机译:目的:确定哮喘儿童(<15岁)口服糖皮质激素的处方中是否存在性别差异。方法:确定了8072名哮喘病患者,其依据是他们接受了吸入性β-肾上腺素受体激动剂,吸入性皮质类固醇,吸入性色甘酸盐/奈多克隆米酸钠,口服黄嘌呤或白三烯拮抗剂的处方。确定男性与女性相比,不同哮喘治疗方法的赔率(OR)和95%置信区间(CI)。结果与结论:与女性哮喘患儿相比,男性哮喘患儿更有可能(OR = 1.37,95%CI = 1.21,1.55,P <0.001)接受口服皮质类固醇的处方,这表明他们患病的可能性可能更大。而不是对疾病的不同管理。在研究期间,男性哮喘儿童不太可能接受抗生素治疗(OR = 0.85,95%CI = 0.77,0.93,P <0.001)。

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