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首页> 外文期刊>British Journal of Clinical Pharmacology >Risk factors for medication misadventure among residents in sheltered housing complexes.
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Risk factors for medication misadventure among residents in sheltered housing complexes.

机译:受庇护的住宅区居民中药物滥用的风险因素。

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AIM: To identify risk factors for unplanned hospitalizations among residents of sheltered housing complexes (SHCs). METHODS: Medication-related risk factors for health outcomes among residents of SHCs in Aberdeen (n = 1137) were assessed using a postal questionnaire. Predictors of unplanned hospitalization/emergency department (ED) visit were identified using logistic regression. RESULTS: Of the 695 (61.1%) responses received, 645 were from residents (mean age 78.2 years) using prescribed medications. One or more risk factors for medication-related problems was seen in 467 (72.4%) respondents; 488 (75.7%) were using medications with high potential for adverse drug reactions (ADRs) in the elderly. Unplanned hospitalizations/ED visits (n = 230) were found to be associated with use of drugs of narrow therapeutic index [P < 0.001; odds ratio (OR) 2.98, 95% confidence interval (CI) 1.69, 5.28]; use of five or more different medications (P = 0.001; OR 2.10, 95% CI 1.34, 3.31); and greater disability (Townsend score) (P = 0.005; OR 1.06, 95% CI 1.02, 1.11). CONCLUSION: Residents of SHCs using drugs of narrow therapeutic index, using five or more different medications, and with greater disability warrant periodic monitoring.
机译:目的:确定庇护下的住房综合体(SHC)居民计划外住院的危险因素。方法:使用邮政调查表评估了阿伯丁(1137)SHC居民中与药物相关的健康结局危险因素。使用logistic回归确定计划外的住院/急诊科(ED)访问的预测因素。结果:在收到的695份答复中(61.1%),有645份来自处方药的居民(平均年龄78.2岁)。 467(72.4%)被调查者发现了一种或多种与药物相关问题的风险因素; 488(75.7%)人使用的是老年人中极有可能出现药物不良反应(ADR)的药物。发现计划外住院/急诊就诊(n = 230)与使用治疗指数狭窄的药物有关[P <0.001;比值比(OR)2.98,95%置信区间(CI)1.69,5.28];使用五种或更多种不同的药物(P = 0.001; OR 2.10,95%CI 1.34,3.31);以及更大的残疾(乡镇得分)(P = 0.005; OR 1.06,95%CI 1.02,1.11)。结论:使用低治疗指数的药物,使用五种或更多不同药物,以及具有更大残疾的SHC居民需要定期监测。

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