Methods in Clinical Pharmacology

摘要

Experimental sciences rely on technical methods. In the case of clinical pharmacology, methods are often used that have been developed by other disciplines, such as analytical chemistry (eg high performance liquid chro-matography, gas chromatography, mass spectrometry), biochemistry/molecular biology (eg radioimmunoassay/ ELISA, Southern/western blotting, PCR/DNA sequencing), physiology (functional surrogates such as blood pressure, forced expiratory volume in 1 second and specific airway conduction), psychology (subjective states such as drowsiness and mood and objective measurements such as reaction times), statistics (eg population PK-PD analyses), epidemiology (eg survival), economics (quality-adjusted life-years) and so on.